Coma and other disorders of consciousness
Jouvet M.
Handbook of Clinical Neurology Vol.3. P. J. Vinken and G. W. Bruyn , eds. North-Holland Publishing Company. Amsterdam,(1969)


Physiopathological basis of coma (introductory remarks)

Nervous structures necessary for consciousness

Periodic physiological dissolution of consciousness: sleep and coma

From experimental to clinical neurophysiology

Physiopathology of nervous lesions responsible for coma

Aetiological classification of comas and of disturbances of consciousness of organic origin

Symptomatological classification of coma

Tentative anatomoclinical classification


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Figure 8 : Diagrammatic anatomoclinical correlation of main forms of coma

On the left: the most common lesions are shown in black on a sagittal section of the encephalon; less frequent lesions shown as dotted areas.
On the right: results of the clinical examination. Black squares indicate a negative response to each test.

  • (1) Akinetic mutism: P3-D3-R1-VI.
  • (2) Decortication syndrome: P5-D1-RI-VI.
  • (3) Upper brainstem lesion: P5-D3-R2 Vl.
  • (4) Brain death: P5-D4-R3-V2. See details in text.

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