Biogenic Amines and the States of Sleep
Michel Jouvet
Science 163 (862) pages : 32-41 (1969)
TABLE OF CONTENTS

Introduction

The Four Major Concepts

Biogenic Amines and the Sleep States

Insomnia Following Selective Decrease of Cerebral Serotonin

The Problem of Paradoxical Sleep

Summary

FIGURES

PRINT
Printable version

Figure 1 : Polygraphic recording of the adult cat, showing waking and the two states of sleep

  1. Waking: muscular activity of the neck (EMG), eye movements (EM), fast low-voltage activity of the occipItal. cortex (CX), and sharp waves in the lateral genicu late (LG) which accompany eye movements.
  2. Slow-wave sleep: decreased muscular activity of the neck, absence of eye movements, high-voltage slow waves on the cortex, and high-voltage geniculate waves which directly precede paradoxical sleep by 1 or 2 minutes
  3. Paradoxical sleep: total disappearance of EMG activity. together with rapid eye movements, fast low-voltage cortical activity. and clusters of high-voltage lateral geniculate waves. Each line represents l minute of recording; amplitude calibra tion, 50 microvolts.

Next page