Paradoxical Sleep - A Study of its Nature and Mechanisms
Michel Jouvet
Progress In Brain Research Vol. 18 Sleep Mechanisms 1965
Evidence of the duality of the states of sleep

(a) EEG and behavioural findings

(b) Phylogenetic findings

(c) Ontogenetic findings

(d) Functional findings

(e) Structural findings

Mechanisms of paradoxical sleep

(a) Producing P.S. as a reflex

(b) Results of deafferentations

(c) Role of the hypothalamus and pituitary

(d) Deprivation of P.S. in the pontile animal

(e) Effects of temperature on P.S. in the pontile animal

(f) Action of gamma-butyrolactone (G.B.L.)

(g) Osmolarity of the blood and paradoxical sleep


(a) Duality of the states of sleep

(b) Mechanisms underlying the appearance of P.S.

Summary and Conclusions



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Figure 20 : Development of pontine and EMG activity during P.S. in the pontine animal without hypothalamus or pituitary

  • (a) 2nd day: monophasic pontine peaks during P.S.
  • (b) 3rd day.
  • (c) 6th day: muscular activity has not entirely disappeared and occurs phasically only during pontine rhythmic activity.

Scale: 1 sec; 50 microV.

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