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Figure 6
WORKING HYPOTHESIS,
proposed by the author to provide a bridge between the
neurophysiology and the biochemistry of sleep, suggests that the normal
state of wakefulness (a) is transformed into light sleep (b) when a secretion
produced by the nuclei of raphe modifies many effects of the reticular
activating system. Paradoxical sleep follows (c) when a second secretion,
produced by the locus coeruleus, supplants the raphe secretion and produces
effects that resemble normal wakefulness except for the loss of muscle
tension.
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