Biogenic Amines and the States of Sleep
Michel Jouvet
Science 163 (862) pages : 32-41 (1969)
TABLE OF CONTENTS

Introduction

The Four Major Concepts

Biogenic Amines and the Sleep States

Insomnia Following Selective Decrease of Cerebral Serotonin

The Problem of Paradoxical Sleep

Summary

FIGURES

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Figure 6 : Three-way correlation of the extent of the destruction of the raphe system

(A and B), the level of serotonin in the brain rostral to the lesion (B and C), and the resulting diminution of both states of sleep (A and C). In A and C, total sleep is represented by dots; paradoxical sleep, by a vertical line; total sleep, by a horizontal bar.