Biogenic Amines and the States of Sleep
Michel Jouvet
Science 163 (862) pages : 32-41 (1969)
TABLE OF CONTENTS

Introduction

The Four Major Concepts

Biogenic Amines and the Sleep States

Insomnia Following Selective Decrease of Cerebral Serotonin

The Problem of Paradoxical Sleep

Summary

FIGURES

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Figure 5 : Relationships between paradoxical sleep and slow wave sleep

(Crosses) Cats that have undergone sham operations; the values for slow-wave sleep and paradoxical sleep are normal. (Black dots) Cats with the raphe system totally or partially destroyed. Note that paradoxical sleep occurs only if the amount of slow-wave sleep is greater than 15 percent. (Triangles) Cats with total bilateral destruction of the nucleus locus coeruleus. Values for slow-wave sleep are normal; paradoxical sleep is com pletely suppressed.

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