Figure 23 : Relationship between P.S. and osmolarity of the blood
Pontile animal with hypothalamic island. Ordinate: Proportion of P.S.
during recording period (calculated per period of 100 min). Abscissa:
Time in minutes and hours. The normal proportion of P.S. (control determined
over 10 days) is 8% (+ 2%). Continuous line: After intravenous injection
(arrow) of 20 ml of 20% hypertonic saline, high levels of P.S. for 5 h.
Broken line: After forcing of a quantity of water 10% of the body weight,
following injection of 2 units ADH. complete disappearance of P.S. for
5 h followed by slow return to normal. Blood Na and K levels were determined
at A, B, C and D (in mequiv/l): before and after injection of saline:
Na: 142-152-168-157; K: 6.4 5.2-6.3 6.2. a b c-d : after forcing of water:
Na: 157-146-138-136-138; K: 6.2-6.6-6.2-5.6 7.2. In this animal injection
of ADH had no effect on the proportion of P.S.