| Sur un cas d'agrypnie (4 mois sans sommeil) au cours d'une maladie de Morvan. Effet favorable du 5-hydroxytryptophane |
| C. Fischer-Perroudon, J. Mouret et M. Jouvet Electroencephalography and Clinical Neurophysiology, 1974, 36: 1-18 |
| IMPRESSION |
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Figure 3 : Sample of characteristic hypnograms
Above: Total insomnia: only 10 min of stage I at 8 a.m. The oblique hatching signals the period during which the patient was walking in the sleep laboratory.
Middle: After 10 g of tryptophan (TRY 10 g per os given at 0,15 a.m.). There is no.significant improvement of sleep.
Below: Recovery of sleep after large dose of DL-5-HTP (1500 mg given per os at 11 p.m and 4.00 a.m.). The occurrence of stages III, IV and PS is especially evident after the second dose of 5-HTP.
Ordinates: E Waking. I,II,III, IV: stages I,II, III and IV. SP: paradoxical sleep.
Abcissae: time in hours